Natrol® Cognium® is powered by a silk protein hydrolysate that has been clinically shown to improve memory and recall in healthy adults. Researchers conducted multiple randomized, double-blind, placebo-controlled studies and published their findings in peer-reviewed journals. The studies can be found below. In these clinical studies, the silk protein hydrolysate in Cognium is referred to as either Brain Factor-7 or BF-7.

Cognium Regular and Extra Strength Clinical Studies

(Click on link below to read study)

  1. “Association between cerebral blood flow and cognitive improvement effectby B. mori extracted compound.” Kor J Seric Sci 2004a; 46(2):77-79. Korean.
  2. “BF-7 improved memory function and protected neurons from oxidative stress.” Kor J Phys Anthropol 2004c;17(4):313-320.Korean.
  3. “The improvement of learning and memory ability of normal persons by BF-7.” Kor J Physiol Pharmacol 2004b Dec; 8:307-312.
  4. “The effect of BF-7 on the ischemia-induced learning and memory deficits.” Kor J Anat 2005; 38(2):181-188. Korean.