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Natrol® Stress & Anxiety DAY/NIGHT formula with Melatonin, 5-HTP and L-Theanine helps reduce the effects that stress and anxiety have on the body and helps establish normal sleep patterns to provide a more restful, relaxing sleep and in turn, better overall health.† 

Product Description

5-HTP (5-Hydroxytryptophan) is a drug-free and naturally occurring plant-derived amino acid that participates in the body’s synthesis of serotonin, the chemical messenger that plays a key role in enhancing mood. Natrol 5-HTP, is the #1 5-HTP brand in America^, and promotes a calm and relaxed mood while helping you maintain a positive outlook.

L-Theanine is derived from green teas and undergoes a process where it is separated from the caffeine. Just like green tea, it increases alpha waves in the brain that are associated with relaxation and calmness.

Melatonin serves as the body’s biological clock, managing the sleep and wake cycles. Age, everyday stress and diet choices induced by busy lifestyles can take a toll on the body’s production of melatonin. Natrol Melatonin, the #1 melatonin brand in America, is a nighttime sleep aid that assists with occasional sleeplessness. It helps to establish normal sleep patterns to give you a more restful, relaxing sleep and in turn, better overall health.

Stress & Anxiety Day Formula

The daytime formula with 5-HTP and vitamins B6, B12 and Folic Acid helps maintain emotional well-being while the amino acid L-Theanine ensures relaxation without making you drowsy.

  • Promotes a calm and relaxed mood
  • Helps maintain a positive outlook
  • 50mg 5-HTP participates in the body’s synthesis of serotonin
  • 50mg L-Theanine ensures calm relaxation
  • 100% drug-free
  • Non-habit forming
  • 100% Vegetarian
Stress & Anxiety Night Formula

The nighttime formula with Melatonin and powerful antioxidants protect your body from oxidative damage induced by a hectic lifestyle, so you can wake up refreshed and ready to tackle the day.

  • 3mg of Melatonin to help you fall asleep faster, stay asleep longer and wake up feeling refreshed
  • 100mg Valerian Extract to promote a natural quality of sleep
  • 30 IU Vitamin E to protect your body from oxidative damage induced by a hectic lifestyle
  • 25 mg Grape Seed Extract, an antioxidant that helps support your cell’s health
  • 72 mg Calcium supports your production of melatonin
  • 800mg L-glutamine, an amino acid helps enhance the state of your sleep
  • 100% drug-free
  • Non-habit forming
  • 100% Vegetarian
Calm yourself and bring down stress and anxiety levels day and night. Go ahead, own your mood and sleep with the uniquely formulated Natrol Stress & Anxiety Day & Night.

Additional Information

Please consult your healthcare professional prior to use if you have or suspect a medical condition, are taking prescription drugs, or are pregnant or lactating.

Individual results may vary.

Product details

Drug Free
Free Of
Milk, Egg, Fish, Crustacean Shellfish, Tree Nuts, Peanuts, Wheat, Yeast, Artificial Colors or Flavors, Added Sugar or Preservatives
Key Ingredients
DAY: 5-HTP, L-Theanine, Vitamin B; NIGHT: Calcium, Grapeseed Extract, L-Glutamine, Melatonin, Valerian
Number of Servings
30 + 30
Serving Size
1 Tablet


Q: What is Natrol Stress & Anxiety DAY/NIGHT Formula? A: Natrol Stress & Anxiety DAY/NIGHT formula is a two formula combo package with clinically tested ingredients designed to calm you by day and night.† 
Q: Is there research to support the Stress & Anxiety DAY/NIGHT formula claims? A: Yes. Natrol Stress & Anxiety DAY/NIGHT formulas were designed to include ingredients that have been experimentally tested. The product claims are based on the supportive data from experimental and clinical studies.† 
Q: Why is the Stress & Anxiety DAY/NIGHT formula divided into day and night doses? A: The formulas were designed to help you get the most out of your days and nights. To achieve this benefit, two separate formulas were needed. Natrol’s DAY formula helps reduce anxiety and supports calm, focused, relaxed and positive mood with 5-HTP and B vitamins. By helping to reduce anxiety, it also promotes a more relaxed transition to evening activities.

The NIGHT formula features Melatonin and L-Glutamine as well as Valerian and Grape Seed extracts. Scientific evidence suggests that ingredients in this formula may help reduce nighttime anxiety so you can fall asleep quickly and stay asleep longer. Powerful antioxidants help your body’s antioxidant system while you are sleeping. 
Q: Is the Melatonin synthetic? A: Yes, melatonin is synthetic.
Q: Do you sell the Stress & Anxiety DAY/NIGHT Formula separately? A: Yes, you can also purchase the day and night formula separately. The day formula for Stress & Anxiety is also known as 5-HTP Mood Positive. The night formula for Stress & Anxiety is also known as Sleep ‘n Restore.
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