Natrol® Cognium® is powered by a silk protein hydrolysate that has been clinically proven to improve memory and concentration. Researchers conducted multiple randomized, double-blind, placebo-controlled studies and published their findings in peer-reviewed journals. The studies can be found below. In these clinical studies, the silk protein hydrolysate in Cognium is referred to as either Brain Factor-7 or BF-7.

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Cognium Clinical Studies

(click on link below to read study)

  1. Association between cerebral blood flow and cognitive improvement effect by B. mori extracted compound. Kor J Seric Sci 2004a; 46(2):77-79. Korean.
  2. BF-7 improved memory function and protected neurons from oxidative stress. Kor J Phys Anthropol 2004c;17(4):313-320.Korean.
  3. The improvement of learning and memory ability of normal persons by BF-7. Kor J Physiol Pharmacol 2004b Dec; 8:307-312.
  4. The effect of BF-7 on the ischemia-induced learning and memory deficits. Kor J Anat 2005; 38(2):181-188. Korean.

Extra Strength Cognium Clinical Studies

(click on link below to read study)

  1. Association between cerebral blood flow and cognitive improvement effect by B. mori extracted compound. Kor J Seric Sci 2004a; 46(2):77-79. Korean.
  2. BF-7 improved memory function and protected neurons from oxidative stress. Kor J Phys Anthropol 2004c;17(4):313-320.Korean.
  3. The improvement of learning and memory ability of normal persons by BF-7. Kor J Physiol Pharmacol 2004b Dec; 8:307-312.
  4. The effect of BF-7 on the ischemia-induced learning and memory deficits. Kor J Anat 2005; 38(2):181-188. Korean.
  5. The Role of BF-7 on Enhancement of Memory and Cognitive Function. Kim, 2004
  6. The Role of BF-7 on Neuroprotection and Enhancement of Cognitive Function. Chae, 2004.
  7. The Improvement of Short and Long-term Memory of Young Children by BF7. Kim, 2010.