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Natrol Health News

New clinical research continues to support a natural way to bolster the body’s immune response

The peer-reviewed journal, Advances in Therapy, recently published the results of a randomized, double- blind, placebo-controlled study1 that found the immune supplement EpiCor® can help reinforce the body’s innate immune response by bolstering salivary immunoglobulin A (sIgA), one of the body’s first lines of defense. Researchers also reported improvements in nasal and sinus health in individuals taking the supplement over the course of 12 weeks. This research builds on already positive findings from earlier controlled trials showing that EpiCor® can help activate crucial immune defense cells (e.g., natural killer cells)2 and help individuals guard their immunity and feel better.3,4  

Epicor® is an all-natural fermentation product of baker’s yeast (Saccharomyces cerevisiae) that has been the subject of both experimental and clinical research documenting its immune-modulating potential. Natrol developed its most recent innovative wellness product, Immune Boost [www.NatrolImmuneBoost.com], using the clinically validated ingredient Epicor® in combination with other vital immune nutrients such as vitamin D, selenium, vitamin C and zinc.

Epicor® is a registered trademark of and manufactured by Embria Health Sciences, LLC, Akeny, IA.

In the first study of its kind, two of nature’s most important nutrient super-stars will take center stage

Scientists at Harvard Medical School and Brigham Women’s Hospital will determine the impact of Omega-3 fish oil and Vitamin D on cardiovascular and cellular health. Funded through the National Institutes of Health, the study—dubbed the Vitamin D and Omega 3 VITAL trial (VITamin D and OmegA-3 TriaL)—will evaluate 20,000 men and women over a period of five years.

Fish oil and vitamin D are two of the most recognized supplements among consumers today. Unfortunately, very few foods naturally contain vitamin D or the omega-3 fats EPA and DHA; therefore, achieving an optimal intake through diet alone can be difficult. Nutrition surveys suggest that the majority of Americans fail to consume enough vitamin D from food sources and dietary supplements combined.5 Furthermore, the usual dietary intake of EPA and DHA in the United States is only about 150 mg per day—not enough for health benefits.6

Natrol has created Fish Oil + Vitamin D3, a convenient once-a-day product that combines 1,000 mg fish oil with high potency vitamin D (1,000 IU) to help consumers achieve a healthy intake of omega-3 fats and vitamin D for optimal health.

Researchers uncover probiotic’s ability to influence immunity at the genetic level

Although the immune bolstering effects of probiotics have been documented in the scientific literature, a recent study has confirmed for the first time that one specific healthy bug, known as Lactobacillus plantarum, works at the genetic level to support the body’s natural immune resistance.7 Scientists found that healthy adults ingesting L. plantarum exhibited a specific gene expression profile in the gastrointesintal tract that favored up-regulation of the body’s response to an immune challenge.

Earlier research has documented the ability of probiotics to help strengthen gut immune defense mechanisms.8 And considering that 70% of the body’s immune system is in the digestive tract,9 it’s really no surprise that ingesting probiotics can impact digestion and help people stay healthy.10

Natrol’s most recent innovative product Probiotic Intestinal Maximum Care features IntestiBiotic™, a proprietary blend of four clinically validated strains.

References

1. Moyad MA, Robinson LE, Kittelsrud JM, et al. Immunogenic yeast-based fermentation product reduces allergic rhinitis-induced nasal congestion: a randomized, double-blind, placebo-controlled clinical trial. Adv Ther. 2009;26(8):795-804. PMID: 19672568

2. Redman K, Bensen K, Jensen G. Final Report 11:  Short term in vivo study analyzing the effects of an acute single dose of 500mg EpiCor® versus a placebo control. Unpublished Research. 2008

3. Jensen G, Patterson K, Barnes J, et al. A double-blind, placebo-controlled, randomized pilot study: consumption of a high-metabolite immunogen from yeast culture has beneficial effects on erythrocyte health and mucosal immune protection in healthy subjects. The Open Nutrition Journal. 2008; 2: 68-75.

4. Moyad M, Robinson L, Zawada E, et al. Effects of a modified yeast supplement on cold/flu symptoms. Urologic Nursing. 2008;28(1):50-56. PMID: 18335698

5. Moore C, Murphy MM, Keast DR, Holick MF. Vitamin D intake in the United States. J Am Diet Assoc. 2004;104:980-983. PMID: 15175600

6. Kris-Etherton PM, Taylor D, Yu-Poth S, et al. Polyunsaturated fatty acids in the food chain in the United States. Am J Clin Nutr. 2000;71:179-188. PMID: 10617969

7. van Baarlen FJ, Troost S, van Hemert C, et al.Differential NF-kappaB pathways induction by Lactobacillus plantarum in the duodenum of healthy humans correlating with immune tolerance.Proc Natl Acad Sci U S A. 2009;106(7):2371-2376.PMID: 19190178

8. Marteau PR, de Vrese M, Cellier CJ, et al. Protection from gastrointestinal diseases with the use of probiotics. Am J Clin Nutr. 2001;73(2):430S-436S. PMID: 11157353

9. Furness JB, Kunze WA, Clerc N. Nutrient tasting and signaling mechanisms in the gut. II. The intestine as a sensory organ: neural, endocrine, and immune responses. Am J Physiol. 1999;277(5 Pt 1):G922-8. PMID: 10564096

10. de Vrese M, Winkler P, Rautenberg P, et al. Effect of Lactobacillus gasseri PA 16/8, Bifidobacterium longum SP 07/3, B. bifidum MF 20/5 on common cold episodes: A double blind, randomized, controlled trial. J Clin Nutr. 2005;24:481-491. PMID: 16054520

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